§Explain
how the binding of transcription factors to promoter regions affects gene
expression and/or the phenotype of the organism
§Explain
the connection between the regulation of gene expression and phenotypic
differences in cells and organisms.
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Tasks:
1
Quizlet Live
Practice Vocabulary
2
Does gene expression
lead to variation? – Argumentation You are to use understanding of gene
regulation, genetics, and heredity to craft a CER. You and your team will
need to be ready to explain your ideas to the class later today.
Modeling the impact
of gene regulation on phenotypes in twins. Using the cards for eukaryotic
gene expression, you are to sequence an event that causes one twin to be
different than another. Use these event cards to sequence the events that
lead to differences in phenotypes between identical twins.
Discussion: Discuss
how environmental influences and gene regulation contribute to the concept of
nature versus nurture and the complexity of phenotypic expression in the model.
3
Notes > Gene Expression and Cell Specialization Let’s go over the impact of gene expression on
phenotypes of organisms.Promoters are
DNA sequences upstream of the transcription start site where RNA polymerase
and transcription factors bind to initiate transcription .Negative regulatory
molecules inhibit gene expression by binding to DNA and blocking
transcription. Gene regulation results in differential gene expression and
influences cell products and function. Certain small RNA molecules have roles
in regulating gene expression.
4
Does gene expression
lead to variation? – Argumentation You are to use understanding of gene
regulation, genetics, and heredity to craft a CER. You and your team will need
to be ready to explain your ideas to the class tomorrow.